Brief Information of the Compound and Protein
Compound Name
2-cyclopropyl-3-[(2,3-dichlorophenyl)methyl]-5-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
    Show/Hide
PubChem ID
CID: 70683337
Canonical SMILES
Clc1cccc(Cn2c(nn3c2nc(cc3=O)N2CCOCC2)C2CC2)c1Cl
    Show/Hide
Compound Formula C19H19Cl2N5O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468 Homo sapiens (Human)  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.5 nM