Brief Information of the Compound and Protein
Compound Name
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-5-ethoxy-2-methyl-N-(2-pyrrolidin-1-ylethyl)aniline
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PubChem ID
CID: 67162897
Canonical SMILES
CCOc1cc(NCCN2CCCC2)c(C)c(c1)N1CCN(CC1)c1ncnc2n[nH]c(Br)c12
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Compound Formula C24H33BrN8O
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 9067 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 56 nM