Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-(4-chlorophenyl)-N-[2-(4-cyclopropyl-4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide
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 PubChem ID
CID: 60150483
SID: 144081118
Canonical SMILES
Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(O)(CC1)C1CC1
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Compound Formula C26H27ClN4O2
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
2
IC50 = 149 nM
   TI
   LI
   LO
   TS