Brief Information of the Compound and Protein
Compound Name
4-N-(2-methylsulfanylphenyl)-2-piperazin-1-yl-8-N-(pyridin-2-ylmethyl)pyrimido[5,4-d]pyrimidine-4,8-diamine
    Show/Hide
PubChem ID
CID: 53348217
SID: 125089948
Canonical SMILES
CSc1ccccc1Nc1nc(nc2c(NCc3ccccn3)ncnc12)N1CCNCC1
    Show/Hide
Compound Formula C23H25N9S
Compound Structure
Protein Name
Ketohexokinase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P50053
Gene Name
KHK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 270 nM
   TI
   LI
   LO
   TS