Brief Information of the Compound and Protein
Compound Name
2-(4-chlorophenoxy)-N-[4-methyl-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-6-yl]propanamide
    Show/Hide
PubChem ID
CID: 70685346
Canonical SMILES
CC(Oc1ccc(Cl)cc1)C(=O)Nc1ccc2nc(nc(C)c2c1)N1CCC(CC1)N1CCCC1
    Show/Hide
Compound Formula C27H32ClN5O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 258 nM
   TI
   LI
   LO
   TS
2
IC50 = 401 nM
   TI
   LI
   LO
   TS