Brief Information of the Compound and Protein
Compound Name
N-[2-(4-ethyl-4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
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PubChem ID
CID: 70683241
Canonical SMILES
CCC1(O)CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1
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Compound Formula C25H27F3N4O4
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
2
IC50 = 116 nM
   TI
   LI
   LO
   TS