Brief Information of the Compound and Protein
Compound Name
3-[5-(5-ethoxy-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,1-diethylurea
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PubChem ID
CID: 135566617
Canonical SMILES
CCOc1cc2[nH]c(nc2cc1F)-c1n[nH]cc1NC(=O)N(CC)CC
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Compound Formula C17H21FN6O2
Compound Structure
Protein Name
Tyrosine-protein kinase ITK/TSK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q08881
Gene Name
ITK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS