Brief Information of the Compound and Protein
Compound Name
1-(4-amino-8-fluoroquinazolin-7-yl)-3,6,6-trimethyl-5,7-dihydroindol-4-one
    Show/Hide
PubChem ID
CID: 25060729
SID: 56397626
Canonical SMILES
Cc1cn(c2CC(C)(C)CC(=O)c12)-c1ccc2c(N)ncnc2c1F
    Show/Hide
Compound Formula C19H19FN4O
Compound Structure
Protein Name
Heat shock protein HSP 90-beta
Protein Classification
Other cytosolic protein
Uniprot ID
P08238
Gene Name
HSP90AB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000261 SK-BR-3 Homo sapiens (Human)  1
1
IC50 = 665 nM
   TI
   LI
   LO
   TS