Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5R)-2-amino-5-cyclopropyl-3-methyl-5-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]imidazol-4-one
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 PubChem ID
CID: 57404339
SID: 136949836
Canonical SMILES
CC#Cc1cncc(c1)-c1cccc(c1)[C@]1(N=C(N)N(C)C1=O)C1CC1
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Compound Formula C21H20N4O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.4 nM