Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-amino-5-[3-(3-chlorophenyl)phenyl]-3-methyl-5-pyrimidin-5-ylimidazol-4-one
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 PubChem ID
CID: 59262316
Canonical SMILES
CN1C(N)=NC(C1=O)(c1cncnc1)c1cccc(c1)-c1cccc(Cl)c1
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Compound Formula C20H16ClN5O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 21000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 830 nM