Brief Information of the Compound and Protein
Compound Name
 Compound Info 
cis-(3RS,4SR)-N-[3,5-Bis(trifluoromethyl)benzyl]-N-methyl-3-phenylpiperidine-4-carboxamide hydrochloride
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 PubChem ID
CID: 57397018
Canonical SMILES
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)[C@H]1CCNC[C@H]1c1ccccc1.Cl
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Compound Formula C22H23ClF6N2O
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.6 nM
   TI
   LI
   LO
   TS