Brief Information of the Compound and Protein
Compound Name
5-[4-(1H-imidazol-2-yl)phenyl]-3-(oxan-4-ylmethyl)-1H-imidazo[4,5-b]pyrazin-2-one
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PubChem ID
CID: 24985717
Canonical SMILES
O=c1[nH]c2ncc(nc2n1CC1CCOCC1)-c1ccc(cc1)-c1ncc[nH]1
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Compound Formula C20H20N6O2
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
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Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  2
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
2
IC50 = 273 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM