Brief Information of the Compound and Protein
Compound Name
4-[5-(4-hydroxyphenyl)-2-oxo-1H-imidazo[4,5-b]pyrazin-3-yl]cyclohexane-1-carboxamide
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Canonical SMILES
NC(=O)[C@H]1CC[C@H](CC1)n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1
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Compound Formula C18H19N5O3
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
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Atypical protein kinase PIKK family
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Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 179 nM