Brief Information of the Compound and Protein
Compound Name
indole-based 7-membered lactam, 23a
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PubChem ID
CID: 44143558
Canonical SMILES
O=C(Nc1cccnc1)c1ccc2cc3C(=O)NCCCn3c2c1
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Compound Formula C18H16N4O2
Compound Structure
Protein Name
Ribosomal protein S6 kinase alpha-3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase RSKb family
>
CAMK protein kinase RSKb subfamily
Uniprot ID
P51812
Gene Name
RPS6KA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 1940 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 240 nM