Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[6-(difluoromethoxy)-4-methylpyridin-3-yl]-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
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 PubChem ID
CID: 25114821
SID: 56438901
Canonical SMILES
CCC(CC)c1cc(C)n2nc(-c3cnc(OC(F)F)cc3C)n(C)c(=O)c12
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Compound Formula C20H24F2N4O2
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P35353
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 8.4 nM
   TI
   LI
   LO
   TS