Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)-N-(4-isopropylphenyl)acetamide
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 PubChem ID
CID: 1150897
SID: 81046146
Canonical SMILES
CC(C)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1
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Compound Formula C18H21N5O3
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily A member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O75762
Gene Name
TRPA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 6200 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000411 IMR-90
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2300 nM