Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[5-chloro-2-[[(3S)-3-[(2-methoxyacetyl)amino]-5,5-dimethyl-2-oxo-3,4-dihydro-1H-1-benzazepin-8-yl]amino]pyrimidin-4-yl]amino]-3-fluoro-N-methylbenzamide
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 PubChem ID
CID: 57398926
Canonical SMILES
CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@H](CC3(C)C)NC(=O)COC)c2)ncc1Cl
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Compound Formula C27H29ClFN7O4
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS