Brief Information of the Compound and Protein
Compound Name
9-(4-chlorophenyl)-15-piperazin-1-yl-8-oxa-2,4,5-triazatetracyclo[11.4.0.02,6.07,11]heptadeca-1(13),3,5,7(11),9,14,16-heptaene
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PubChem ID
CID: 57392443
Canonical SMILES
Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1
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Compound Formula C23H20ClN5O
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.3 nM