Brief Information of the Compound and Protein
Compound Name
5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide
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PubChem ID
CID: 53475321
SID: 126520222
Canonical SMILES
Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1
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Compound Formula C27H25ClN4O2
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000229 SW1353 Homo sapiens (Human)  1
1
EC50 = 350 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
EC50 = 350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM