Brief Information of the Compound and Protein
Compound Name
(E,Z)-5-((5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)furan-2-yl)methylene)-2-thioxoimidazolidin-4-one
    Show/Hide
PubChem ID
CID: 727340
Canonical SMILES
O=C1NC(=S)N/C1=C/c1ccc(-c2ccc3c(c2)COC3=O)o1
    Show/Hide
Compound Formula C16H10N2O4S
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
>
Other ion channel
>
Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 6200 nM
   TI
   LI
   LO
   TS