Brief Information of the Compound and Protein
Compound Name
(E,Z)-5-((5-(1-Oxo-1,3-dihydroisobenzofuran-5-yl)-1H-indol-2-yl)methylene)-2-thioxoimidazolidin-4-one
    Show/Hide
Canonical SMILES
O=C1NC(=S)N/C1=C/c1cc2cc(-c3ccc4c(c3)COC4=O)ccc2[nH]1
    Show/Hide
Compound Formula C20H13N3O3S
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
>
Other ion channel
>
Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS