Brief Information of the Compound and Protein
Compound Name
4-N-(3-bromophenyl)-6-(naphthalen-1-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
    Show/Hide
PubChem ID
CID: 3008950
Canonical SMILES
Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3cccc4ccccc34)[nH]c2n1
    Show/Hide
Compound Formula C23H18BrN5
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P17948
Gene Name
FLT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000073 A-498 Homo sapiens (Human)  1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19200 nM