Brief Information of the Compound and Protein
Compound Name
3-chloro-4-[[7-(1H-1,2,4-triazol-5-yl)benzo[c][2,6]naphthyridin-5-yl]amino]phenol
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PubChem ID
CID: 136042193
Canonical SMILES
Oc1ccc(Nc2nc3c(cccc3c3cnccc23)-c2nnc[nH]2)c(Cl)c1
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Compound Formula C20H13ClN6O
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000091 MV4-11 Homo sapiens (Human)  1
1
EC50 = 1500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 39 nM