Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-(5-cyano-6-methylpyridin-2-yl)oxy-2,2,4,4-tetramethylcyclobutyl]imidazo[1,2-a]pyrimidine-3-carboxamide
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 PubChem ID
SID: 134420505
Canonical SMILES
Cc1nc(O[C@H]2C(C)(C)[C@H](NC(=O)c3cnc4ncccn34)C2(C)C)ccc1C#N
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Compound Formula C22H24N6O2
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 144 nM
   TI
   LI
   LO
   TS