Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(8S,9R,10S,11S,13S,14S,17R)-17-[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]-9-fluoro-11,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
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 PubChem ID
CID: 57400817
Canonical SMILES
C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CSc1nc2ccccc2s1
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Compound Formula C28H32FNO4S2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 535 nM
   TI
   LI
   LO
   TS
CL000246 NCI-H292
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.6 nM