Brief Information of the Compound and Protein
Compound Name
rac-cis-1-Ethyl-N-{2-Methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]}benzyl)-3-phenyl-4-piperidinamine hydrochloride
    Show/Hide
PubChem ID
CID: 57393952
Canonical SMILES
CCN1CC[C@H](NCc2cc(-n3nnnc3C(F)(F)F)ccc2OC)[C@H](c2ccccc2)C1.Cl
    Show/Hide
Compound Formula C23H28ClF3N6O
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 1.9 nM
   TI
   LI
   LO
   TS