Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,4S)-N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-1-methylsulfonyl-3-phenylpiperidin-4-amine
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 PubChem ID
CID: 57402690
Canonical SMILES
COc1ccc(cc1CN[C@H]1CCN(C[C@H]1c1ccccc1)S(C)(=O)=O)-n1nnnc1C(F)(F)F
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Compound Formula C22H25F3N6O3S
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.075 nM
   TI
   LI
   LO
   TS