Brief Information of the Compound and Protein
Compound Name
2-[(2R)-4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]-1H-indole-5-carbonitrile
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PubChem ID
CID: 57392781
Canonical SMILES
COc1ccc(F)cc1C(C)(C)C[C@@](O)(Cc1cc2cc(ccc2[nH]1)C#N)C(F)(F)F
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Compound Formula C23H22F4N2O2
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 6 nM