Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(fluoromethyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-yladamantane-1-carboxamide
    Show/Hide
 PubChem ID
CID: 57403172
Canonical SMILES
COc1ccccc1N1CCN(CCN(C(=O)C23CC4CC(CC(CF)(C4)C2)C3)c2ccccn2)CC1
    Show/Hide
Compound Formula C30H39FN4O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 4.27 nM
   TI
   LI
   LO
   TS
2
Ki = 1.82 nM
   TI
   LI
   LO
   TS