Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N,N-dimethyl-2-[4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]phenoxy]ethanamine
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 PubChem ID
CID: 11682470
SID: 16786650
Canonical SMILES
CN(C)CCOc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1
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Compound Formula C23H23N5O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM