Brief Information of the Compound and Protein
Compound Name
5-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)-2-methylbenzyl)thiazolidine-2,4-dione
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PubChem ID
CID: 46216676
SID: 96071033
Canonical SMILES
Cc1cc(Oc2ncc(C(F)(F)F)cc2Cl)ccc1CC1SC(=O)NC1=O
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Compound Formula C17H12ClF3N2O3S
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  2
1
EC50 = 87.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 177.83 nM
   TI
   LI
   LO
   TS
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  1
1
Ki = 69.18 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 54.95 nM
   TI
   LI
   LO
   TS