Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-[6-amino-5-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-3-yl]pyrazol-1-yl]-N-[2-(dimethylamino)ethyl]-2-methylpropanamide
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 PubChem ID
CID: 11656580
SID: 16760076
Canonical SMILES
CC(Oc1cc(cnc1N)-c1cnn(c1)C(C)(C)C(=O)NCCN(C)C)c1c(Cl)ccc(F)c1Cl
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Compound Formula C24H29Cl2FN6O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 65.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 59.7 nM