Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(oxan-4-yl)pyrazol-4-yl]pyridin-2-amine
    Show/Hide
 PubChem ID
CID: 11612136
SID: 16714992
Canonical SMILES
CC(Oc1cc(cnc1N)-c1cnn(c1)C1CCOCC1)c1c(Cl)ccc(F)c1Cl
    Show/Hide
Compound Formula C21H21Cl2FN4O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 39.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 38.3 nM