Brief Information of the Compound and Protein
Compound Name
2-[[2-amino-5-[4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]phenyl]pyridin-3-yl]oxymethyl]benzonitrile
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PubChem ID
CID: 54576374
SID: 129980946
Canonical SMILES
Nc1ncc(cc1OCc1ccccc1C#N)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1
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Compound Formula C29H31N5O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 6500 nM