Brief Information of the Compound and Protein
Compound Name
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1H-pyrazol-5-yl)pyridin-2-amine
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PubChem ID
CID: 11667754
SID: 129983914
Canonical SMILES
CC(Oc1cc(cnc1N)-c1cc[nH]n1)c1c(Cl)ccc(F)c1Cl
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Compound Formula C16H13Cl2FN4O
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 597 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 348 nM