Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[4-[6-amino-5-[(2-chloro-3,6-difluorophenyl)methoxy]pyridin-3-yl]phenyl]-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone
    Show/Hide
 PubChem ID
CID: 54576601
SID: 129981163
Canonical SMILES
Nc1ncc(cc1OCc1c(F)ccc(F)c1Cl)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1
    Show/Hide
Compound Formula C28H29ClF2N4O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 880 nM