Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[4-[6-amino-5-[(4-tert-butylphenyl)methoxy]pyridin-3-yl]phenyl]-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone
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 PubChem ID
CID: 54576376
SID: 129980948
Canonical SMILES
CC(C)(C)c1ccc(COc2cc(cnc2N)-c2ccc(cc2)C(=O)N2CCC[C@@H]2CN2CCCC2)cc1
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Compound Formula C32H40N4O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8530 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 980 nM