Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-amino-5-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-3-yl]-N-(2-pyrrolidin-1-ylethyl)benzamide
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 PubChem ID
CID: 21110871
SID: 129983918
Canonical SMILES
CC(Oc1cc(cnc1N)-c1ccc(cc1)C(=O)NCCN1CCCC1)c1c(Cl)ccc(F)c1Cl
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Compound Formula C26H27Cl2FN4O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 114 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 75 nM