Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2-amino-6-(3-methoxypyridin-2-yl)quinolin-3-yl]-N-(3,3-dimethylbutyl)-2-methylpropanamide
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 PubChem ID
CID: 53465993
SID: 126492175
Canonical SMILES
COc1cccnc1-c1ccc2nc(N)c(CC(C)C(=O)NCCC(C)(C)C)cc2c1
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Compound Formula C25H32N4O2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 97 nM