Brief Information of the Compound and Protein
Compound Name
rac-2-({3-[Bis(4-fluorophenyl)methyl]-4-oxopiperidin-1-yl}methyl)benzonitrile hydrochloride
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PubChem ID
CID: 56678485
Canonical SMILES
Cl.N#Cc1ccccc1CN1CCC(=O)C(C(c2ccc(F)cc2)c2ccc(F)cc2)C1
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Compound Formula C26H23ClF2N2O
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 6.1 nM
   TI
   LI
   LO
   TS