Brief Information of the Compound and Protein
Compound Name
rac-1-(5-Amino-2-methoxybenzyl)-3-(diphenylmethyl)piperidin-4-one dihydrochloride
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PubChem ID
CID: 23025460
Canonical SMILES
COc1ccc(N)cc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1.Cl.Cl
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Compound Formula C26H30Cl2N2O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 5.9 nM
   TI
   LI
   LO
   TS