Brief Information of the Compound and Protein
Compound Name
4-[4-({(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-hexyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]-N-methylbenzamide hydrochloride
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PubChem ID
CID: 56678577
Canonical SMILES
CCCCCCN1C(=O)[C@@H]([C@H](O)C2CCCCC2)NC(=O)C12CCN(Cc1ccc(Oc3ccc(C(=O)NC)cc3)cc1)CC2.Cl
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Compound Formula C36H51ClN4O5
Compound Structure
Protein Name
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000149 HOS Homo sapiens (Human)  1
1
IC50 = 35000 nM
   TI
   LI
   LO
   TS