Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[2-[4-[14-(dimethylsulfamoylamino)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-5-yl]pyrazol-1-yl]acetyl]morpholine
    Show/Hide
 PubChem ID
CID: 53310546
SID: 124769962
Canonical SMILES
CN(C)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(CC(=O)N2CCOCC2)c1
    Show/Hide
Compound Formula C25H26N6O5S
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM