Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-N-[5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]propane-2-sulfonamide
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 PubChem ID
CID: 53310542
SID: 124769958
Canonical SMILES
Cn1cc(cn1)-c1cnc2ccc3ccc(NS(=O)(=O)C(C)(C)C)cc3c(=O)c2c1
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Compound Formula C22H22N4O3S
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 31 nM