Brief Information of the Compound and Protein
Compound Name
 Compound Info 
14-(dimethylsulfamoylamino)-5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
    Show/Hide
 PubChem ID
CID: 16222392
SID: 24904874
Canonical SMILES
CN(C)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1
    Show/Hide
Compound Formula C20H19N5O3S
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM