Brief Information of the Compound and Protein
Compound Name
4-[5-(2-methoxyethoxy)pyridin-3-yl]-5,14,18-triazatetracyclo[9.7.0.02,7.012,17]octadeca-1(11),2,4,6,12(17)-pentaen-13-one
    Show/Hide
PubChem ID
CID: 56679974
Canonical SMILES
COCCOc1cncc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCCc2cn1
    Show/Hide
Compound Formula C23H24N4O3
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 180 nM