Brief Information of the Compound and Protein
Compound Name
Pyrrolopyridine, 23
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PubChem ID
CID: 11992146
SID: 17491274
Canonical SMILES
Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
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Compound Formula C18H14FN3O
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
EC50 = 2700 nM
   TI
   LI
   LO
   TS
2
IC50 = 8900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 372 nM
2 IC50 = 126 nM
3 IC50 = 560 nM