Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(2-morpholin-4-ylethoxy)phenyl]spiro[3,5,13,17-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,11(16)-pentaene-14,1'-cyclopropane]-12-one
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 PubChem ID
CID: 56676658
Canonical SMILES
O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(nc-34)-c3ccc(OCCN4CCOCC4)cc3)c12
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Compound Formula C27H29N5O3
Compound Structure
Protein Name
 Protein Info 
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 180 nM