Brief Information of the Compound and Protein
Compound Name
3-(2-(2-methylthiazol-4-yl)ethynyl)-5-nitroiodobenzene
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PubChem ID
CID: 54582378
Canonical SMILES
Cc1nc(cs1)C#Cc1cc(I)cc(c1)[N+]([O-])=O
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Compound Formula C12H7IN2O2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 1.75 nM
   TI
   LI
   LO
   TS
2
Ki = 1.84 nM
   TI
   LI
   LO
   TS