Brief Information of the Compound and Protein
Compound Name
6-(2-phenylethynyl)-N-propan-2-ylpyridine-3-carboxamide
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PubChem ID
CID: 54581607
Canonical SMILES
CC(C)NC(=O)c1ccc(nc1)C#Cc1ccccc1
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Compound Formula C17H16N2O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 62 nM
   TI
   LI
   LO
   TS
2
Ki = 7100 nM
   TI
   LI
   LO
   TS